Back to trials
completed
Not Applicable

NCT02298725

Individual Metabolism and Physiology Signature Study

Sponsored by USDA, Western Human Nutrition Research Center

Summary

To determine if consumption of different diet plans that both are nutritionally-adequate and provide energy to maintain body weight, alters fasting insulin concentrations, shifts other common clinical markers of metabolic disease risk, and affects metabolomic profiles that reflect glucose, lipid, and amino acid metabolism.

Eligibility Criteria

Inclusion Criteria: * Premenopausal by self-report * Body Mass Index 25-39.9 kg/m2 * Fasting glucose ≥100 and \<126 mg/dL and/or * Oral Glucose Tolerance Test (OGTT) 2-hour glucose ≥140 and \<199 mg/dL and/or * Quantitative insulin sensitivity check index (QUICKI) score \<0.315 and/or * Homeostasis Model Assessment (HOMA) \>3.67, or log HOMA \>0.085 and/or * Glycated Hemoglobin HbA1c ≥5.7 and \<6.5fasting glucose ≥100 and \<126 mg/dL and/or * Fasting triglyceride concentrations \>150 mg/dL and/or * LDL cholesterol \>100 mg/dL and/or * HDL cholesterol \<40 mg/dL. Exclusion Criteria: * BMI \<25 and \>39.9 kg/m2 * Presence of any metabolic diseases, by self-report * Gastrointestinal disorders by self-report * Presence of cancer or other serious chronic disease by self-report * Current use of prescribed or over the counter weight loss medications * Pregnant * Lactating * Current use of tobacco * Moderate or strenuous physical activity \>30 min/day, 5 or more days per week * Weight change \>5% of body weight during the previous 6 months * Dietary restrictions that would interfere with consuming the intervention foods

Locations (2)

Western Human Nutrition Research Center

Davis, California, United States

Clinical Translational Science Center

Sacramento, California, United States

Why you can trust this information
Registry sourcesclinicaltrials_gov
Source last updated3/25/2026
Clintriva indexed9/27/2026, 9:22:12 PM
Registry records1
Relationships needing review0

Identity-resolution confidence concerns registry/entity resolution and does not determine clinical eligibility.

Interested in this trial?

Express your interest and we'll connect you with the trial team.

Your selected profile and contact information may be shared with an authorised trial site, sponsor, or Clintriva coordination team for trial contact and pre-screening. Expressing interest does not mean you are eligible or enrolled.

Quick Facts
Start DateDec 16, 2014
CompletionMar 30, 2017
Enrollment0/52
CountryUnited States

Conditions

Insulin Resistance
Metabolic Syndrome X
Obesity
View on registry
Clintriva
GDPR Controls Mapped HIPAA Safeguards Mapped NHS DSP Controls Mapped SOC 2 Controls Mapped

© 2026 Clintriva. All rights reserved.